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Latest news

August 2024: Landon Hodge presents his work at the Veterinary Scholars Symposium in Minneapolis

Well done, Landon! In such a short time, Landon got lots of exciting results with the Acinetobacter baumannii bovine isolates and also succeeded in screening some bacterial genes for their role in adhesion, invasion, and intracellular multiplication of human isolate ABC141. Congratulations on mastering the genetics of our difficult multi-drug resistant strains!

Thank you Boehringer Ingelheim, for funding Landon with a Veterinary Summer Scholars Grant.

 

June 2024: Welcome to Landon Hodge, Summer Scholar SVM student

Landon has joined our lab for the summer to help identify the bacterial genes involved in intracellular Acinetobacter baumannii and study recent veterinary clinical isolates from Wisconsin. We thank SVM for this excellent program and Boehringer Ingelheim for funding Landon with a Veterinary Summer Scholars Grant.

 

January 2024: New publication on the importance of taxonomy: Ochrobactrum Is Not Brucella!

Moreno E et al. (2023) If You’re Not Confused, You’re Not Paying Attention: Ochrobactrum Is Not BrucellaJournal of Clinical Microbiology 61(8): e00438-23. doi: 10.1128/jcm.00438-23

 

IBA meeting in Oslo, Norway

Suzana participates at the IBA National Graduate School in Infection Biology and Antimicrobials meeting in Oslo, Norway (October 2023). Excellent oral and poster presentations from the graduate students.

 

Charline participates in the Cold Spring Harbor meeting

Charline presenting her poster

Charline Debruyne participates in the Microbial Pathogenesis and Host Response Meeting at the Cold Spring Harbor. She presented a poster on the intracellular niche of Acinetobacter baumannii clinical strains.

 

The Salcedo Lab has moved!

Suzana by the Vet School Bucky

The Salcedo Lab has moved from France to the University of Wisconsin-Madison, School of Veterinary Medicine!
We are just getting started preparing our lab space to welcome everyone. Charline and Lison will stay a bit longer in the lab of our long-time friend and collaborator Matteo Bonazzi at IRIM in Montpellier.

Time for a new website, lab name and logo…

Logo and lab name: intrapath

 

 

 

 

Congratulations to our collaborators Stephan Göttig et al. for beautiful work showing the impact of Acinetobacter baumannii on mitochondria. We are excited to have contributed to this nice story!

Leukert L, Tietgen M, Krause FF, Schultze TG, Fuhrmann DC, Debruyne C, Salcedo SP, Visekruna A, Wittig L, Göttig S. (2023) Infection of Endothelial Cells with Acinetobacter baumannii Reveals Remodelling of Mitochondrial Protein Complexes. Microbiology Spectrum  Jun 15;11(3):e0517422. doi: 10.1128/spectrum.05174-22.

News archive

Goodbye party

July 2023

Goodbye party to close the lab in Lyon! Eleven wonderful years of collaborations, friendships, lots of laughs, and a few tears.

 

Graduate student dinner

June 2023

Lab dinner with previous graduate studentsWonderful dinner with all the previous graduate students from the lab: Stephanie Gagne, Jean-Baptiste Luizet, Arthur Louche, Morgane Roussin Lison Cancade-Veyre, Charline Debruyne and Amandine Blanco. Just missing Paul Imbert who is now in London and that I met a couple of weeks after.

 

 

Just published, the Nyx effectors targeting nuclear functions

January 2023

Just published! Kudos to Arthur and Amandine for this achievement.

Composite image showing the detection of translocated Nyx in infected cells, the structural domain relevant for its function, the delocalization of nucleolar proteins and of SENP3.Extensive collaborative work identifying two new Brucella effectors targeting the host nuclear functions. We have named them Nyx, in honor of the Greek goddess of the night, daughter of Chaos, to illustrate the scientific path to their discovery!
We highlight that NyxA and NyxB display a novel nucleomodulatory function that promotes perturbation of the subcellular localization of nucleolar proteins during bacterial infection. Structural studies identified the key interacting domains mediating Nyx targeting of the host de-SUMOylase SENP3, needed for efficient intracellular multiplication of Brucella abortus. Click here for article.